The focus of my group is on the study of the intestinal microbes and how they interact with the host. This relationship is fundamental to our health and, when perturbed...
Inflammasomes are multi-protein complexes that are responsible for the induction of proinflammatory cytokines and inflammatory cell death. They are unique in innate...
Broadly, my group investigates the coevolution of pathogens and hosts’ adaptive immunity. We use computational and mathematical tools to test hypotheses and to advance...
Our group studies microbial population diversity, ecology, and evolution. We focus primarily on freshwater and marine systems, and we use a combination of laboratory...
With our expertise in computation and microbiology we create and employ advanced 'omics and wet-lab strategies to study the ecology and evolution of naturally...
Immunological niches in the digestive system
We study how immune homeostasis is maintained in the digestive system, and how its failure can lead to diseases such as...
The primary goal of my laboratory is to understand how the innate immune system detects retroviral infection and initiates virus-neutralizing adaptive immune responses...
Research
My broad interest is in how organisms adapt to a changing environment. My lab studies this in the context of pathogen-host interactions using the gram negative...
Laboratory safety, especially biosafety, is a critical component of research activities conducted in the Biological Sciences Division at the University of Chicago (UC...
