Dr. Missiakas’s research program examines the Gram-positive pathogens Staphylococcus aureus and Bacillus anthracis. This program seeks to appreciate the biogenesis of the envelope of these microorganisms as well as the secretion of their virulence factors and host pathways targeted by these pathogens.
Université of Paris XI
Orsay, France
Ph.D. - Biochemistry
1991
Orthogonal cell division mediated by PcdA organizes surface virulence factors to drive staphylococcal abscess community formation.
Orthogonal cell division mediated by PcdA organizes surface virulence factors to drive staphylococcal abscess community formation. Cell Rep. 2026 Aug 17; 45(8):117861.
PMID: 42606939
Selective fluorination of Fc glycans enhances antibody-mediated effector functions.
Selective fluorination of Fc glycans enhances antibody-mediated effector functions. Proc Natl Acad Sci U S A. 2026 Mar 24; 123(12):e2530653123.
PMID: 41849397
Orthogonal cell division organizes surface virulence factors to drive staphylococcal abscess community formation.
Orthogonal cell division organizes surface virulence factors to drive staphylococcal abscess community formation. bioRxiv. 2026 Mar 12.
PMID: 41959123
Type VIIb secretion system recruits the dedicated cell wall hydrolase EssH to enable effector secretion by Staphylococcus aureus.
Type VIIb secretion system recruits the dedicated cell wall hydrolase EssH to enable effector secretion by Staphylococcus aureus. mBio. 2026 04 08; 17(4):e0319625.
PMID: 41744680
Role of staphylococcal EzrA as a molecular organizer of cell division.
Role of staphylococcal EzrA as a molecular organizer of cell division. bioRxiv. 2026 Feb 21.
PMID: 41757093
Examining the role of IgA in a persistent model of Staphylococcus aureus colonization.
Examining the role of IgA in a persistent model of Staphylococcus aureus colonization. PLoS Pathog. 2026 Jan; 22(1):e1013924.
PMID: 41604437
Polymer-lipid hybrid nanoparticle enhances mRNA delivery and T cell-mediated immunity.
Polymer-lipid hybrid nanoparticle enhances mRNA delivery and T cell-mediated immunity. bioRxiv. 2026 Jan 24.
PMID: 41648598
Dual-mode ClfA-targeting DARPin biologics protect against diverse methicillin-resistant Staphylococcus aureus strains.
Dual-mode ClfA-targeting DARPin biologics protect against diverse methicillin-resistant Staphylococcus aureus strains. bioRxiv. 2026 Jan 12.
PMID: 41542421
Type VIIb secretion system recruits a dedicated cell wall hydrolase EssH to enable effector secretion by Staphylococcus aureus.
Type VIIb secretion system recruits a dedicated cell wall hydrolase EssH to enable effector secretion by Staphylococcus aureus. bioRxiv. 2025 Oct 30.
PMID: 41278976
The signal peptide of staphylococcal protein A alters the multimeric states of PepV.
The signal peptide of staphylococcal protein A alters the multimeric states of PepV. Microbiol Spectr. 2025 12 02; 13(12):e0177825.
PMID: 41143410