Molecules record the history of coevolution between life and earth environments. Our group develops and applies cutting-edge analytical techniques to explore the relationships between cellular processes and global biogeochemical cycles. A major focus is proteomics, which probes the molecules directly responsible for biochemical activity.
The FleQ-FleN circuit balances flagellar number against fitness in Pseudomonas aeruginosa.
The FleQ-FleN circuit balances flagellar number against fitness in Pseudomonas aeruginosa. mBio. 2026 Sep 09; 17(9):e0036026.
PMID: 42554464
Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation in Pseudomonas putida.
Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation in Pseudomonas putida. Proc Natl Acad Sci U S A. 2025 Nov 25; 122(47):e2513479122.
PMID: 41259139
Regulatory Plasticity and Metabolic Trade-offs Drive Adaptive Evolution of Alternative Flagellar Configurations in Pseudomonas aeruginosa.
Regulatory Plasticity and Metabolic Trade-offs Drive Adaptive Evolution of Alternative Flagellar Configurations in Pseudomonas aeruginosa. bioRxiv. 2025 Jul 29.
PMID: 40766384
Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida.
Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida. ACS Synth Biol. 2025 07 18; 14(7):2739-2752.
PMID: 40607986
Mechanisms of Polyethylene Terephthalate Pellet Fragmentation into Nanoplastics and Assimilable Carbons by Wastewater Comamonas.
Mechanisms of Polyethylene Terephthalate Pellet Fragmentation into Nanoplastics and Assimilable Carbons by Wastewater Comamonas. Environ Sci Technol. 2024 Oct 29; 58(43):19338-19352.
PMID: 39360733
Disproportionate Carbon Dioxide Efflux in Bacterial Metabolic Pathways for Different Organic Substrates Leads to Variable Contribution to Carbon-Use Efficiency.
Disproportionate Carbon Dioxide Efflux in Bacterial Metabolic Pathways for Different Organic Substrates Leads to Variable Contribution to Carbon-Use Efficiency. Environ Sci Technol. 2024 Jun 25; 58(25):11041-11052.
PMID: 38860668
Energy flux couples sulfur isotope fractionation to proteomic and metabolite profiles in Desulfovibrio vulgaris.
Energy flux couples sulfur isotope fractionation to proteomic and metabolite profiles in Desulfovibrio vulgaris. Geobiology. 2024 May-Jun; 22(3):e12600.
PMID: 38725144
Author Correction: Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism.
Author Correction: Complex regulation in a Comamonas platform for diverse aromatic carbon metabolism. Nat Chem Biol. 2024 Mar; 20(3):392.
PMID: 38316916
Erratum for Wilkes et al., "Analogous Metabolic Decoupling in Pseudomonas putida and Comamonas testosteroni Implies Energetic Bypass to Facilitate Gluconeogenic Growth".
Erratum for Wilkes et al., "Analogous Metabolic Decoupling in Pseudomonas putida and Comamonas testosteroni Implies Energetic Bypass to Facilitate Gluconeogenic Growth". mBio. 2024 Mar 13; 15(3):e0335223.
PMID: 38315009
Seasonal shifts in community composition and proteome expression in a sulphur-cycling cyanobacterial mat.
Seasonal shifts in community composition and proteome expression in a sulphur-cycling cyanobacterial mat. Environ Microbiol. 2023 11; 25(11):2516-2533.
PMID: 37596970