Faculty

Tatyana Golovkina, PhD

Professor of Microbiology
Committee on Genetics, Genomics and Systems Biology
Committee on Immunology
Committee on Microbiology
Research and Scholarly Interests: viruses, bacteria, commensal microbes
Websites: Research Network Profile
Contact: tgolovki@uchicago.edu
Graduate Programs: Genetics, Genomics & Systems Biology, Immunology, Microbiology, UChicago Biosciences

Golovkina's laboratory studies mechanisms of host-pathogen and host-commensal microbe interactions.

Moscow State University
Moscow, Former USSR
PhD - Biochemistry, Virology
1985

H2-O deficiency in B cells or dendritic cells drives retrovirus-neutralizing antibody responses.
H2-O deficiency in B cells or dendritic cells drives retrovirus-neutralizing antibody responses. J Virol. 2026 Sep 22; 100(9):e0085326.
PMID: 42671555

Cohousing or cross-fostering followed by cohousing does not normalize the microbiomes of genetically distinct adult mice.
Cohousing or cross-fostering followed by cohousing does not normalize the microbiomes of genetically distinct adult mice. Cell Rep. 2025 Oct 28; 44(10):116402.
PMID: 41066229

Microbiota does not influence tumor development in two models of heritable cancer.
Microbiota does not influence tumor development in two models of heritable cancer. mBio. 2025 03 12; 16(3):e0386624.
PMID: 39969175

Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice. PLoS Pathog. 2024 06; 20(6):e1012306.
PMID: 38843309

The endogenous Mtv8 locus and the immunoglobulin repertoire.
The endogenous Mtv8 locus and the immunoglobulin repertoire. Front Immunol. 2024; 15:1345467.
PMID: 38504980

Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer.
Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer. bioRxiv. 2023 Oct 12.
PMID: 37873087

A single dominant locus restricts retrovirus replication in YBR/Ei mice.
A single dominant locus restricts retrovirus replication in YBR/Ei mice. J Virol. 2023 08 31; 97(8):e0068523.
PMID: 37578238

Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ.
Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ. Viruses. 2023 01 29; 15(2).
PMID: 36851600

Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ.
Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ. bioRxiv. 2023 Jan 11.
PMID: 36711645

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus.
Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 09 13; 40(11):111341.
PMID: 36103821

View All Publications

The KT Jeang Retrovirology prize
University of Chicago
2020

Fellow of American Association for the Advancement of Science
2019

Fellow of the American Academy of Microbiology
2018

Cancer Research Institute (CRI) 2000 Hillsdale Fund, Inc. Greensboro, N.C.
2000

Oliver and Jennie Donaldson Charitable Trust
2000

V Foundation Scholar
1997

Cancer Research Institute Postdoctoral Fellowship Award
1993 - 1995

Prize of All-Union Young Scientists competition (together with S.V. Litvinov)
1987